[pdf] Organic Synthesis: Concepts, Methods, Starting Materials. With a Foreword by E. J. Corey

The Logic of Chemical Synthesis The title of this three-part volume derives from a key theme of the book—the logic underlying the rational analysis of complex synthetic problems. Although the book deals almost exclusively with molecules of biological origin, which are ideal for developing the fundamental ideas of multistep synthetic design because of their architectural complexity and variety, the approach taken is fully applicable to other types of carbon-based structures. Part One outlines the basic concepts of retrosynthetic analysis and the general strategies for generating possible synthetic pathways by logical reduction of molecular complexity. Systematic retrosynthetic analysis and the concurrent use of multiple independent strategies to guide problem solving greatly simplify the task of devising a new synthesis.

This book discusses the crucial place that assumptions hold in conceptualizing, implementing, and evaluating development programs. It suggests simple ways for stakeholders and evaluators to 1) examine their assumptions about program theory and environmental conditions and 2) develop and carry out effective program monitoring and evaluation in light of those assumptions. A survey of evaluators from an international development agency reviewed the state of practice on assumptions-aware evaluation. This 2nd edition has been updated with further illustrations, case studies, and frameworks that have been researched and tested in the years since the first edition.

Alexander L. George was one of the most productive and respected political scientistsof the late twentieth century. He and his wife, Juliette George, wrote one of the firstpsychobiographies, and Professor George went on to write seminal articles and booksfocusing on political psychology, the operational code, foreign policy decisionmaking,case study methodology, deterrence, coercive diplomacy, policy legitimacy, and bridgingthe gap between the academic and policymaking communities. This book is the firstand only one to contain examples of the works across these fields written by AlexanderGeorge and several of his collaborators.

AMERICAN DEMOCRACY IS AT RISK