[share_ebook] Chemical Carcinogenesis (current Cancer Research)

This book is a collection of in-depth chapters on many aspects of contemporary cancer treatment. The information in this book is designed for cancer clinicians and interested readers to whom this knowledge is important for focusing research and improving patient outcomes.

This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy.

This book focuses on innovative treatment options for breast cancer, including surgery, radiotherapy, systemic therapy and of course immunotherapy that is changing outcomes in some aggressive breast cancer histotypes. Subsequent chapters also address the ongoing emerging research in the screening, diagnostics, and management of all subtypes of breast cancers. All current landscapes and future perspectives in each molecular subtype: luminal, HER2-positive, and triple-negative breast cancers are discussed within the different chapters.

This book reviews the applications of polyphenols in cancer treatment. The initial chapter of the book classifies different polyphenols and discusses their biological and chemical properties. The subsequent chapters then explore the diverse role of polyphenols in modulating signal transduction pathways in cancer including, cellular proliferation, differentiation, apoptosis, inflammation, angiogenesis, and metastasis.

The focus of this book is to describe the current understanding of the interactions between the nervous system and cancer and the use of this information in the treatment and prevention of cancer. Author and noted researcher Boris Mravec presents a clearly written and well-illustrated monograph on this rapidly developing new field. The book begins with an exploration of the basic concepts supporting the neurobiology of cancer, discusses the ways in which the nervous system affects all the hallmarks of cancer, delves extensively into stress and cancer, covers the etiopathogenetic consequences of the neurobiology of cancer, the implications for cancer prevention and treatment, and looks at future directions in the field.

Molecularly-Targeted Therapy for Childhood Cancer is a comprehensive exploration of the molecular aspects of childhood cancers that are currently being targeted therapeutically or are in the early phases of development. Each chapter describes key molecular characteristics of hematopoietic malignancies and solid tumors in children and young adults that are fundamental to the etiology, survival and drug resistance of these cancers as well as able to serve as tumor selective pathways for treatment.