Basic Clinical Pharmacokinetics

This volume delivers the latest information on biotransformation and other pharmacokinetic parameters required to assess drug safety in drug discovery and development. Drug metabolism and pharmacokinetics (DMPK) is considered a rational strategy for the design, optimization, and selection of successful drug candidates in the pre-clinical stages of drug discovery. This book discusses recent advances in in-silico tools and in vitro/in vivo experimental techniques applied in pharmacokinetic, metabolomic, and bioanalytical studies.

The purpose of this book is to show some of the advances in the identification of pharmacological properties of natural and synthetic molecules that may be used in the development of pharmacological therapies destined for the treatment of illness and disorders that affect the wellness of humans.

Pharmacokinetics, Pharmacodynamics

by Stephen H. Curry (Author), Robin Whelpton (Author)

Clinical Bioequivalence Study, BA/BE, Types of Study designs, Crossover Design, Parallel Design, AUC, Cmax, Tmax, PK/PD