Botulinum Toxin

The book covers the fundamentals of botulinum toxins, including improvements in our understanding of their molecular structure and mechanism of action, it covers the production and formulation of botulinum toxins for clinical applications.

Bladder injection of onabotulinumtoxinA for the treatment of urinary incontinence due to neurogenic detrusor overactivity has recently been approved by regulatory agencies in several EU countries and by the FDA in the United States. This is the first book to focus on the practical application of botulinum toxin (BoNT) in the genitourinary tract. It covers in detail applications of BoNT in the bladder and the prostate and pelvic floor, with reviews of the latest clinical series and techniques in both adults and children. Appendices containing easy-to-read instructions for patients undergoing bladder and prostate BoNT injections are included, in addition to procedural guidelines for nursing staff. The book is written in a concise, clinically relevant style by two leading pioneers in the field, who were the first to undertake comprehensive basic research into the mechanisms underlying the efficacy and potential uses of BoNT within the lower urinary tract.

The aim of this book is to ensure a safe understanding and use of botulinum toxin in medicine. Known indications, contraindications, diversity, comparative effects between subtypes, limits, allergies, treatments, adverse reactions, nonresponsiveness, and new investigations will be described. Botulinum toxin can be currently used in nearly every specialty.

Taking exception from previous publications and reviews, this handbook boldly knits botulinum toxin therapy indications in both dystonia and spasticity. As well, clinicians and students alike will find the book useful in content and relevance to contemporary times.

Anatomical Diagnosis: the GPS of the Botulinum Toxin Treatment

Clinical Applied Anatomy Special for Botulinum Toxin Treatment