Direct Mechanisms in Cholesterol Modulation of Protein Function by Avia Rosenhouse-DantskerEnglish | PDF,EPUB | 2019 | 170 Pages | ISBN : 3030142647 | 43.93 MB
In this book, renowned scientists describe how cholesterol interacts with various proteins. Recent progress made in the high-resolution visualization of cholesterol-protein interactions using crystallography and cryogenic electron microscopy has substantially advanced the knowledge of critical features. These features enable specific recognition of the cholesterol molecule by proteins, a process that was built on earlier studies using binding assays, computational modeling and site-directed mutagenesis.