Hepatecellular Carcinoma Animal Model

This book covers broad but important aspects of animal modeling for scientific medicine as well as for translational systems and biological sciences. Alternative methods such as cell culture and in vitro experiments that do not require the sacrifice of an animal are encouraged for scientific and medical studies.

This superbly illustrated atlas provides step-by-step descriptions of surgical procedures to the airways based on use of the sheep as an animal model, which has been demonstrated scientifically to be comparable to the human. The procedures covered – tracheotomy, laryngotracheoplasty, slide tracheoplasty, tracheal reconstruction,

This superbly illustrated atlas provides step-by-step descriptions of surgical procedures to the airways based on use of the sheep as an animal model, which has been demonstrated scientifically to be comparable to the human. The procedures covered – tracheotomy, laryngotracheoplasty, slide tracheoplasty, tracheal reconstruction, partial cricotracheal reconstruction, and main endoscopic techniques – are relevant to a range of frequent surgical indications, such as stenosis, laryngotracheomalacia, and tracheal tumor. The book is the first to describe such surgery on the basis of this animal model and includes a full description of preparation of the model. The practical guidance provided will equip surgical trainees with the knowledge required before embarking on these procedures in humans, but will also be highly relevant to more experienced surgeons wishing to upgrade their skills. The book is the outcome of a successful collaboration between the Head and Neck Surgery Departments of the University Hospital of Modena and the Bambino Gesù Hospital in Rome.

This superbly illustrated atlas provides step-by-step descriptions of surgical procedures to the airways based on use of the sheep as an animal model, which has been demonstrated scientifically to be comparable to the human.

This book presents a comprehensive reference that reflects the latest scientific research being done in a variety of medical and biological fields utilizing animal models.
Thanks to animal models, our knowledge of biology and medicine has increased enormously over the past decades, leading to significant breakthroughs that have had a direct impact on the prevention, management and treatment of a wide array of diseases.

This book is the first digital atlas of the degu brain with microscopic features simultaneously in Nissl sections and magnetic resonance imaging (MRI). As an experimental animal model, the degu contributes to a variety of medical research fields in diabetes, hyperglycemia, pancreatic function, and adaptation to high altitude, among others. Recently the degu has gained increasing importance in the field of neuroscience, particularly in studies evaluating the relationship between sociality and cognitive brain functions, and in studies pertaining to the evolutional aspects of the acquisition of tool-use abilities.

This book provides an overview of the biology and biochemistry of peroxisomes, and discusses the contribution of these organelles to peroxisomal and neurodegenerative diseases.