Neoadjuvant Treatment of Mismatch Repair–deficient Colon Cancer — Clinically Meaningful?

This eighth volume in the essential Springer series of cutting-edge contributions in stem cell and cancer stem cell research features the work of 85 authors based in more than a dozen nations. It provides scientists in this vital field with the latest data and techniques, enhancing our knowledge base of the causes, diagnosis, and cell-based treatment of major human diseases including cancer, as well as therapies targeting debilitating injuries to human tissue and organs. The volume’s six sections are arranged thematically, covering stem cell culture, bone marrow stem cells, mesenchymal stem cells, the reprogramming and differentiation of stem cells, treatments, and transplantation.

This book provides the most current advancements in the medical care of glioma patients, accompanied by clinical cases. Clinical implementations of the new multilayered integrated diagnosis of gliomas according to WHO CNS5 are also demonstrated here. New adjuvant therapies, such as chemotherapy/targeted therapy, immunotherapy, and physiotherapy, are discussed in the book. The book also covers the applications of genomics and epigenomics of gliomas in clinical practice. In essence, this book shows the management of gliomas with new treatment modalities, which can prolong the overall survival time of patients fighting glioma.

This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments.

Understanding the foundation of credit repair