Vogel Comparative Bio Mechanics

This book offers a comprehensive and timely overview of the latest developments in the field of biomechanics and extensive knowledge of tissue structure, function, and modeling. Gathering chapters written by authoritative scientists, it reports on a range of continuum and computational models of solids, and related experimental works, for biomechanical applications. It discusses cutting-edge advances such as constitutive modeling and computational simulation of biological tissues and organs under physiological and pathological conditions, and their mechanical characterization. It covers innovative studies on arteries, heart, valvular tissue, and thrombus, brain tumor, muscle, liver, kidney, and stomach, among others. Written in honor of Professor Gerhard A. Holzapfel, the book provides specialized readers with a thorough and timely overview of different types of modeling in biomechanics, and current knowledge about biological structures and function.

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The vitality of the cardiovascular system, which consists of the heart, vas­ culature, and blood, depends on its response to a host of complex stimuli, including biological, chemical, electrical, mechanical, and thermal. The focus of this book, however, is on the response of the heart and arteries to mechanical loads from the perspective of nonlinear solid mechanics. Through my own research in this field, I have come to realize that study­ ing the complex responses of cardiovascular cells, tissues, and organs nec­ essarily requires a combined theoretical, experimental, and computational approach. Theory is needed to guide the performance and interpretation of experiments as well as to synthesize the results; experiment is needed to study the responses of the system to well-controlled loads and to test can­ didate hypotheses and theories; and due to the geometric and material non­ linearities inherent to cardiovascular mechanics, computation is needed to analyze data as well as to solve boundary and initial value problems that correspond to either experimental or in vivo conditions. One of the primary goals of this book is to introduce together basic analytical, experimental, and computational methods and to illustrate how these methods can and must be integrated to gain a more complete understanding of the bio­ mechanics of the heart and vasculature. Despite the focus on cardiovascu­ lar mechanics, the fundamental methods, indeed many of the specific results, are generally applicable to many different soft tissues.

This book presents a comparative study on the static responses of the Euler-Bernoulli beam governed by nonlocal theories, including the Eringen’s stress-gradient beam theory, the Mindlin’s strain-gradient beam theory, the higher-order beam theory and the peridynamic beam theory. Benchmark examples are solved analytically and numerically using these nonlocal beam equations, including the simply-supported beam, the clamped-clamped beam and the cantilever beam. Results show that beam deformations governed by different nonlocal theories at different boundary conditions show complex behaviors. Specifically, the Eringen’s stress-gradient beam equation and the peridynamic beam equation yield a much softer beam deformation for simply-supported beam and clamped-clamped beam, while the beam governed by the Mindlin’s strain-gradient beam equation is much stiffer.

This book (Vol. - I) presents select proceedings of the first Online International Conference on Recent Advances in Computational and Experimental Mechanics (ICRACEM 2020) and focuses on theoretical, computational and experimental aspects of solid and fluid mechanics.