Biophysical Thermodynamics of Intracellular Processes Molecular Machines of The Living Cell

This book presents a comprehensive molecular theory of the living cell based on over thirty concepts, principles and laws imported from thermodynamics, statistical mechanics, quantum mechanics, chemical kinetics, informatics, computer science, linguistics, semiotics, and philosophy.

The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine.

The essence of a major revolution in cell physiology – the first since the cell was recognized as the basic unit of life a century and a half ago – is presented and alternative theories are discussed in this text.

Nano-biotechnology crosses the boundaries between physics, biochemistry and bioengineering, and has profound implications for the biomedical engineering industry.