Crohn's Disease Tersigni

This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases.

The second edition of this book updates, reviews, and discusses the latest findings on the pathophysiology, diagnosis, and management of cardiovascular disease in the older patient. It explains the physiological changes associated with the normal aging process that may lead to the development of disease, to adverse consequences once disease develops, and which alter the risk-benefit equation for medical and other interventions designed to diagnose, assess, and treat cardiovascular disease. Chapters address key issues in the management of cardiovascular disease in the elderly including prevention, coronary artery disease, valvular disease, hypertensive disease, arrhythmias, and interventions. Wherever possible, the authors take an evidence-based approach to recommendations and rely heavily on clinical trials. The value of lifestyle changes in the aging population, the use of primary and secondary prevention strategies, treatments, and complications are also discussed.

This book discusses the extra-intestinal manifestations of Crohn’s disease, recent advances in the diagnosis and treatment of Crohn’s disease, the role of partial enteral nutrition and apheresis in Crohn’s disease, and how Crohn’s disease is treated in Chinese medicine.