Homocysteine in Protein Structurefunction And Human Disease Chemical Biology of Homocysteinecontaining Proteins

This book provides readers with a comprehensive overview of peroxisomes and their role in human diseases. It starts by describing the history of peroxisome research and then examines in detail the current understanding of the biogenesis and function of peroxisomes. It then focuses on peroxisomal disorders and the involvement of peroxisomes in cancer and age-related diseases, discussing in detail the use of model organisms to elucidate the pathogenesis of peroxisomal disorders and the physiological importance of peroxisomal proteins.

This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models. Reflecting the latest technology for generating induced pluripotent stem cells (iPS cells) and their initial characterization, the book explores techniques invaluable both for studies of disease-specific cell types and for their potential applications in regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.

This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models. Reflecting the latest technology for generating induced pluripotent stem cells (iPS cells) and their initial characterization, the book explores techniques invaluable both for studies of disease-specific cell types and for their potential applications in regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.

“Ñusta Carranza Ko's exciting new book deftly challenges the conventional wisdom, showing through detailed case studies of Peru, Uruguay, and South Korea that domestic political factors dominate over international advocacy in explaining long term adherence to–or backsliding from–international human rights and transitional justice norms. Carranza Ko should be commended for an important contribution to international relations and political science.”

“Ñusta Carranza Ko's exciting new book deftly challenges the conventional wisdom, showing through detailed case studies of Peru, Uruguay, and South Korea that domestic political factors dominate over international advocacy in explaining long term adherence to–or backsliding from–international human rights and transitional justice norms. Carranza Ko should be commended for an important contribution to international relations and political science.”