Metabolomic

This volume delivers the latest information on biotransformation and other pharmacokinetic parameters required to assess drug safety in drug discovery and development. Drug metabolism and pharmacokinetics (DMPK) is considered a rational strategy for the design, optimization, and selection of successful drug candidates in the pre-clinical stages of drug discovery. This book discusses recent advances in in-silico tools and in vitro/in vivo experimental techniques applied in pharmacokinetic, metabolomic, and bioanalytical studies.

This book is mainly for researchers interested in the new developments and applications of metabolomics. It is important for physicians using metabolomic approaches in the diagnosis of diseases or treatment, and for postgraduate students starting their research projects on metabolomics.

This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.