Ntroduction to Probability Models Por Sheldon M. Ross

Welcome to new territory: A course in probability models and statistical inference. The concept of probability is not new to you of course. You've encountered it since childhood in games of chance-card games, for example, or games with dice or coins. And you know about the "90% chance of rain" from weather reports. But once you get beyond simple expressions of probability into more subtle analysis, it's new territory. And very foreign territory it is. You must have encountered reports of statistical results in voter sur­ veys, opinion polls, and other such studies, but how are conclusions from those studies obtained? How can you interview just a few voters the day before an election and still determine fairly closely how HUN­ DREDS of THOUSANDS of voters will vote? That's statistics. You'll find it very interesting during this first course to see how a properly designed statistical study can achieve so much knowledge from such drastically incomplete information.

The purpose of this book is to provide a sound introduction to the study of real-world phenomena that possess random variation. It describes how to set up and analyse models of real-life phenomena that involve elements of chance. Motivation comes from everyday experiences of probability, such as that of a dice or cards, the idea of fairness in games of chance, and the random ways in which, say, birthdays are shared or particular events arise.

Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from "neutral evolution." The final chapter studies the evolution of whole genomes by chromosomal inversions, reciprocal translocations, and genome duplication.

Welcome to new territory: A course in probability models and statistical inference. The concept of probability is not new to you of course. You've encountered it since childhood in games of chance-card games, for example, or games with dice or coins. And you know about the "90% chance of rain" from weather reports.

Probability Models is designed to aid students studying probability as part of an undergraduate course on mathematics or mathematics and statistics. It describes how to set up and analyse models of real-life phenomena that involve elements of chance. Motivation comes from everyday experiences of probability via dice and cards, the idea of fairness in games of chance, and the random ways in which, say, birthdays are shared or particular events arise. Applications include branching processes, random walks, Markov chains, queues, renewal theory, and Brownian motion. No specific knowledge of the subject is assumed, only a familiarity with the notions of calculus, and the summation of series. Where the full story would call for a deeper mathematical background, the difficulties are noted and appropriate references given. The main topics arise naturally, with definitions and theorems supported by fully worked examples and some 200 set exercises, all with solutions.

This book introduces and studies a number of stochastic models of subsistence, communication, social evolution and political transition that will allow the reader to grasp the role of uncertainty as a fundamental property of our irreversible world. At the same time, it aims to bring about a more interdisciplinary and quantitative approach across very diverse fields of research in the humanities and social sciences.