Selective Activation of Drugs by Redox Processes

The subject of dioxygen activation and homogeneous catalytic oxidation by metal complexes has been in the focus of attention over the last 20 years.

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy.

Using a case-based approach, the Ninth Edition of Applied Therapeutics: The Clinical Use of Drugs enables students to master the fundamentals of drug therapeutics. All the contributors are leading clinicians with many years of evidence-based care. As students progress through the text, they will learn the basics of common diseases and disorders and develop practical problem-solving skills for devising and implementing successful drug treatment regimens.

This practical manual and standard reference work provides an authoritative source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying an unknown drug in a pharmaceutical product, in a sample of tissue or body fluid from a living patient or in postmortem material. It is intended to be a useful requirement for all forensic and crime laboratories, toxicologists, clinical and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.

Using a case-based approach, the Ninth Edition of Applied Therapeutics: The Clinical Use of Drugs enables students to master the fundamentals of drug therapeutics. All the contributors are leading clinicians with many years of evidence-based care. As students progress through the text, they will learn the basics of common diseases and disorders and develop practical problem-solving skills for devising and implementing successful drug treatment regimens.

The modular structure of the text, and the transparency of its organization, make it easy for instructors to choose their own path through the material and for students to revise; or for working scientists using the book as an up-to-date reference to find the topics they want, and as much of the conceptual context of any individual topic as they may need.