Supporr Resistance

This book discusses antibiotic resistance and some of the organisms that pose immediate, serious, and alarming dangers. It highlights the need for a broader, more comprehensive approach to fighting bacterial infections, which may involve non-compound techniques (other than standard antibacterial drugs) that target bacteria or the host, such as antibodies, probiotics, phytobiotics, and vaccinations.

This timely book discusses antimicrobial drug resistance, specifically, the resistance against the beta-lactam class of antibiotics by Gram-Negative bacteria. The book is broadly divided into five sections. The first section describes the underlying mechanisms of antimicrobial resistance in Gram-negative bacteria. It gives an insight into the beta-lactamases, their types, classification, inhibitors, etc.

Antibiotics have drastically improved the health and life expectancy of humans, yet the abrupt increase of antibiotic usage for animals, agriculture and healthcare has induced antimicrobial resistance. Antimicrobial resistance is leading to resurgence of deadly infectious diseases, calling for new cures. This book presents advanced therapies based on new and complementary drugs, and alternative techniques and strategies, such as phages, probiotics, flavonoids, essential oils, cellulose, peptides, nano delivery, iron starvation and vaccines.

This book contains information on epidemiology, resistance mechanisms, and alternative ways to curtail S. aureus infection, as well as future research opportunities.

‘At a time when authoritarianism is resurgent and democracy is under threat globally, this timely book shines a light on a critical but underappreciated driver
of democratization: ordinary citizens.’
—Maria J. Stephan, Director, Program on Nonviolent Action, USIP, USA.

A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance
ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs.