Bioisosteres in Medicinal Chemistry, Volume 54 by Nathan Brown, Raimund Mannhold, Hugo Kubinyi and Gerd Folkers
English | 2012-10-15 | ISBN: 3527330151 | PDF | 256 pages | 3,4 MB
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.