ABC Transporters and Multidrug Resistance by Ahcène Boumendjel, Jean Boutonnat, Jacques RobertEnglish | PDF | 2009 | 456 Pages | ISBN : 0470227346 | 9.5 MB
A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance
ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs.