Mutation Detection

Birmingham Children's Hospital, NHS Trust, UK. Comprehensive step-by-step guide presents a large number of PCR-based mutation detection methods described to date. Features new techniques of DNA array analysis and experimental methods such as conformation-sensitive gel electrophoresis.

Mutation detection is increasingly undertaken in a wide spectrum of research areas: in medicine it is fundamental in isolating disease genes and diagnosis, and is especially important in cancer research; in biology, commercially important genes can be identified by the mutations they contain.

1Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations.

The book is an excellent reference collection of the research conducted by different workers on induced mutagenesis, worldwide, for more than 80 years. One can get almost all mutation breeding references at one place. The book gives a coherent and concise account of all the important and relevant aspects related to induced mutagenesis with an emphasis on recent developments in the field of crop improvement. The references have been arranged crop wise and important topic wise which deal with not only classical mutation breeding but also spontaneous mutations, somaclonal variations, nanoparticles, and relevant modern aspects.