Next Generation Sequencing

This book written by experts covers various aspects of Next generation sequencing (NGS) including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. The book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.

by Wei Wu (Editor), Hani Choudhry (Editor)

Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequencing methods largely extended the use of tag-based approaches as the tag lengths perfectly match with the short read length of highly parallel sequencing reactions.