Sars

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

It is with great pleasure that we introduce the first volume of Birkhäuser Advances in Infectious Diseases.This book series will focus on relevant t- ics of microbiology and infectious diseases with emphasis (as much as p- sible) on emerging pathogens and related diseases.The series will also stress the inter-disciplinarity of the field and include “modern“ aspects such as progress and new approaches in molecular biology, clinical aspects and modern insights relevant to human and veterinary medicine.

It is with great pleasure that we introduce the first volume of Birkhäuser Advances in Infectious Diseases.This book series will focus on relevant t- ics of microbiology and infectious diseases with emphasis (as much as p- sible) on emerging pathogens and related diseases.The series will also stress the inter-disciplinarity of the field and include “modern“ aspects such as progress and new approaches in molecular biology, clinical aspects and modern insights relevant to human and veterinary medicine.