Systemic Diagnosis

Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies.

This book represents the culmination of the efforts of a group of outstanding experts in vasculitis from all over the world, who have endeavored to draw themselves into this volume by keeping both the text and the accompanying figures and tables lucid and memorable.

In the current era, evidence-based medicine and various supporting technologies dominate everyday clinical practice, according to a disease-centred, as opposed to patient-centred, approach. They have obviously improved the clinical management of diseases and it is therefore unreasonable to think of a medicine in which they are not considered fundamental. In fact, the strength of the new medicine should be to adapt scientific knowledge to a specific clinical case.

The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships.

The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships.