Theoretical Biology of The Cell

The good acceptance of this textbook is an indication that it has served its purpose. The present edition has been prepared in order to cover the main progress achieved in the five years that have elapsed since the first edition. The structure of the book remains essentially the same but a con­ siderable amount of new material has been introduced, particularly in certain areas such as the genetics of immunoglobulins and T cell receptor, the regulation of the immune response, hypersensitivity reactions, and cellular immunology. Today, immunology is essential for biologists in general and in particular for physicians, veterinarians, and pathologists. The great progress and diversification that has taken place in the last few years is due to its enormous value both for the understanding of theoretical biology and for the practical resolution of biochemical, genetic, pathological, and biological problems. Greatly contributing to this progress have been relatively sophisticated techniques, such as immunofluorescence, radioimmune assay, transmission electron micro­ scopy, scanning electron microscopy, isoelectric focusing, quantitative cytofluorimetry, affinity chromatography, and techniques that allow separation of the different lymphocyte subpopulations.

The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology.