Xenotransplantation

In this volume, the focus is on islet transplantation, interesting topics dealing with corneal and peripheral nerve transplantation and decellularization are covered.

This title provides an illuminating examination of the current state of xenotransplantation – grafting or transplanting organs or tissues between members of different species – and how it might move forward into the clinic.

This volume is dedicated to the progress in the preclinical trials strongly affected not only the xenotransplantation study itself but regeneration studies to use pigs as a scaffold to foster human induced pluripotent stem cells.

This book describes general glycobiology in emphasizing the structures, biosynthesis, glycosylation and distribution of the glycans and xenogenic glycoantigens in eukaryotic cells of mammals including mouse, swine, chimpanzee and human. In the middle, I have focused on topics in xenotransplantation glycobiology and expand descriptions of allogenic and xenoantigenic transplantation to open the dawn in insights into the origin of life. One of the biological diversity, named species diversity, is a phenomenon environmentally adapted from the evolutionary process for long period. The distinct structures of glycans discriminate each organism and are the essential molecular basis of the discrimination and difference between the organisms, giving an incompatibility between the different species. Diversity and variations in carbohydrate chain structures between family, species, kingdoms and domains mark the global pattern and signs of immune self- and non-self recognition.