Anticancer Drug Development Guide

This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. "

There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration.

This book provides a detailed review of how oncology drug development has changed over the past decade, and serves as a comprehensive guide for the practicalities in setting up phase I trials. The book covers strategies to accelerate the development of novel antitumor compounds from the laboratory to clinical trials and beyond through the use of innovative mechanism-of-action pharmacodynamic biomarkers and pharmacokinetic studies.