Assay Design

This unique book describes newly discovered proteolytic enzymes and their biological function. In many cases, these enzymes are targets for new drug discovery in order to provide new therapeutic approaches to control human diseases and/or metabolic conditions.

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Strater is a well log and borehole plotting software program that imports your data from a multitude of sources (database files, data files, LAS files, ODBC, and OLE DB data sources). Strater provides innumerable ways to graphically display your data. All the logs are fully customizable to suit your needs. Design and save template and scheme files to make log creation efficient and consistent, create multi-page continuous logs, and quickly display new borehole logs. Utilize the header and footer panes to store all the information about the logs, such as well number, driller, location, method, company name, and company logo. The flexibility Strater offers is unparalleled.

The evaluation of potential mutagenic activity is a critical step in the assessment of the safety of both new and pre-existing chemical types. In Genetic Toxicology: Principles and Methods, expert contributors help to satisfy the demand for education in this tremendously important area of study.

Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction.

This book presents modern and classic analytical approaches that are crucial for the biochemical and functional characterization of the archetypal protein, glyceraldehyde-3-phosphate dehydrogenase (GAPDH). The distinguishing feature of the book is that it covers, in addition to other methods, some of the uncommon but valuable techniques as well. For example, in-gel visualization of enzyme activity, immunoblotting protocols for native (non-denatured) proteins, and proteins resolved by pH-gradient [IEF-isoelectrofocusing], etc. These expedient methods are relevant and vital for the verification of biochemical properties of GAPDH, or similar protein of interest.