Cancer Studies

Endometrial cancer is a hormone-dependent cancer with an increasing incidence that is estimated to continue to grow over the next several years. It is typically treated with surgery and/or chemo-/radiation therapy. The clinical benefit of hormone therapies for advanced and recurrent endometrial cancers underlines the need to examine their characteristics (particularly, steroid hormone receptor expression and functions) to assess how they can be used better. Furthermore, a critical phase that can drive clinicians’ therapeutic choices is histopathological and molecular classification. Thus, a current challenge is to integrate IHC markers with molecular tests to identify prognostic groups. Moreover, the observations of the immunosuppressive nature of the endometrial cancer environment are leading to studies that assess therapies with the aim to boost the immune response, which might represent significant potential in the treatment of the disease. For this reason, current and ongoing studies are trying to improve clinical responses through immunotherapy strategies, either alone or combined with classic treatments.

The worldwide cancer burden will double over the next two decades, with the number of new cancer diagnoses increasing in all regions of the world. However, it is estimated that around 40% of all cancers are preventable through the appropriate application of existing epidemiological and public health knowledge, and with further research this proportion will increase considerably. This edited volume explores the role of place in cancer prevention and how geospatial tools can be used to support this globally important goal. Its chapters detail many aspects of the application of geospatial science to cancer control, including quantifying exposure to environmental carcinogens, access to screening services, the importance of partnership building, and more through a variety of geographically diverse case studies. The book also offers background on geospatial modeling tools and methods for adding spatial analysis to cancer surveillance systems. The book is rooted firmly in the notion that geography significantly influences the accumulation of cancer risks (at the individual and community level) that are modifiable through policy, regulatory, and behavioral changes.

Oncology is a field characterized as “medicine of high complexity” and cancer is generally regarded as a complex system. Therefore, it cannot be classified and treated according only to its biology. Even though research on the biology of cancer has increased and more studies have been published, the related sociological, political and economic dimensions, as well as mathematical models that predict whether this condition will take one course or another, have often been neglected. The Invisible Hand of Cancer—The Complex Force of Socioeconomic Factors in Oncology Today unfolds the variables behind the biological disease, exploring the social aspects and presenting cancer as a model inside of the Complexity Theory.

The worldwide cancer burden will double over the next two decades, with the number of new cancer diagnoses increasing in all regions of the world. However, it is estimated that around 40% of all cancers are preventable through the appropriate application of existing epidemiological and public health knowledge, and with further research this proportion will increase considerably. This edited volume explores the role of place in cancer prevention and how geospatial tools can be used to support this globally important goal. Its chapters detail many aspects of the application of geospatial science to cancer control, including quantifying exposure to environmental carcinogens, access to screening services, the importance of partnership building, and more through a variety of geographically diverse case studies. The book also offers background on geospatial modeling tools and methods for adding spatial analysis to cancer surveillance systems. The book is rooted firmly in the notion that geography significantly influences the accumulation of cancer risks (at the individual and community level) that are modifiable through policy, regulatory, and behavioral changes.

The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis); 2) Translational perspective on hepatocellular carcinoma; 3) Brachytherapy for endometrial cancer; 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer

This is the third, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings in lung cancer and other intrathoracic malignancies. Lung cancer remains the major cancer killer in both sexes worldwide. It is so despite significant progress in recent decades in both diagnostic and treatment approaches. New biological and technological advances in this field are now faster incorporated in the overall decision-making process and are bringing fast and substantial improvements in both survivals and quality of life of lung cancer patients. Optimized patient-oriented approaches are reality of the third decade of this millennium and thoracic oncologists strive towards nothing but seamlessly delivering it in a continuous battle with lung cancer.