Decoding The Antibody Repertoire

Decoding the Antibody Repertoire: High Throughput Sequencing of Multiple Transcripts from Single B Cells

Decoding the Antibody Repertoire: High Throughput Sequencing of Multiple Transcripts from Single B Cells By Brandon DeKosky
English | PDF | 2017 | 105 Pages | ISBN : 3319585177 | 3 MB

This thesis outlines the development of the very first technology for high-throughput analysis of paired heavy and light-chain antibody sequences, opening an entirely new window for antibody discovery and the investigation of adaptive immune responses to vaccines and diseases.