Dna Replication

This book offers to readers current trends in the field of DNA replication. The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero.

The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.

This book covers a wide range of aspects and issues related to the field of DNA replication. The reader will gain an overview of our current understanding of DNA replication and related cellular processes, and useful resources for further reading.

Editors: Kaplan, Daniel L. (Ed.)
​Focus on replication initiation, a complex and highly regulated step of replication
Concentrate on eukaryotes, with relevance to humans and disease
Reveal in detail the molecular mechanisms of initiation, including protein function and regulation

This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades.

This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage.