Hepatotoxicity

This book provides a comprehensive view of the methodologies used for the study of liver toxicity encountered throughout the whole life cycle of a drug, from drug discovery, to clinical trial, post-marketing, and even clinical practice. Organized into six sections, the first section introduces the mechanisms contributing to drug-induced liver toxicity.

This book provides a comprehensive overview of the use of animal models for amyotrophic lateral sclerosis, hepatotoxicity, liver fibrosis/cirrhosis, visceral hyperalgesia, female reproduction, and more.

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. The book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.