The Physical Foundation of Protein Architecture
World Scientific Publishing Company; 1st edition | January 15, 2002 | ISBN-10: 9810247109 | 150 pages | PDF | 5.5 Mb
A protein requires its own three-dimensional structure for its biological activity. If a chemical agent is added, the biological activity is lost, and the three-dimensional structure is destroyed to become a random coil state. But when the chemical agent is removed, the biological activity is recovered, implying that the random coil state turns back into the original complex structure spontaneously.