Latent Tuberculosis Infection

Every year, 10 million people fall ill with tuberculosis (TB) in the world, and of those, 1.5 million people die even though it is a preventable and curable disease. As a result, TB remains the world’s leading infectious cause of death. On the other hand, in industrialized countries, the TB incidence has fallen to a historic low, and clinicians’ experience with TB diminished significantly in recent years. Additional challenges for clinicians include atypical presentation of TB in the immunocompromised, especially among the elderly, and an increasing number of patients with drug-resistant TB.

This volume explores such topics as mechanisms associated with increasing trends of drug-resistant tuberculosis (TB), the development of anti-mycobacterial drugs, genotyping tools, diagnosis and treatment of latent tuberculosis infection, and more.

This book discusses critical issues related to the treatment of HIV infection and related co-infections and challenges in adherence and discordancy. New vaccine approaches discussed may provide the ultimate solution for eradication. Sharing knowledge from various experts in medical and basic sciences improves the quality of care for this persistent global threat. This book discusses emerging advances in HIV-AIDS management to support strategies for control and elimination.

Tuberculosis is an ancient disease, but it's not a disease of history.