Molecular Biology of The Gene

The long-awaited new edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double-helix. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline, giving both historical and basic chemical context. Divided into four parts: Genetics and Chemistry, Central Dogma, Regulation, and Methods. For college instructors, students, and anyone interested in molecular biology and genetics.

The unraveling of the biology and disease mechanisms of the parathyroid has taken great strides in the recent few years. Parathyroid molecular biology is the first book to describe in detail, recent studies and discoveries in the field.

The unraveling of the biology and disease mechanisms of the parathyroid has taken great strides in the recent few years. Parathyroid molecular biology is the first book to describe recent studies and discoveries in the field in detail. Key topics addressed include: The study of the molecular biology of the parathyroid hormone gene and its regulation by calcium, phosphate, and vitamin D The generation of mice with genetic deletions of the parathyroid, as well as mice which fail to develop the parathyroid gland The parathyroid's connection to the calcium receptor and its effects, such as regulation of PTH secretion, gene expression, and proliferation The genetic mutations leading to diseases of decreased or excessive activity of the parathyroid The mechanisms of actions associated with patients with chronic renal failure and the development of markedly excessive activity of the parathyroid that causes severe bone disease This book will be essential reading to everyone interested in the latest developments in this burgeoning field.