Physical Biology of The Cell

The Present book is aimed at providing a readable account of physical methods and results required to measure cell adhesion and interpret experimental data.

This book covers the recently developed understanding of Electro-Mechano-Biology (EMB) in which the focus is primarily on the couplings between the electric and mechanical fields. The emphasis lies on the analytical and computational aspects of EMB at the cellular level. The book is divided into two parts. In the first part, the author starts by defining and discussing the relevant basic aspects of the electrical and mechanical properties of cell membranes. He provides an overview of some of the ways analytical modelling of cell membrane electrodeformation (ED) and electroporation (EP) appears in a variety of contexts as well as a contemporary account of recent developments in computational approaches that can feature in the theory initiative, particularly in its attempt to describe the cohort of activities currently underway. Intended to serve as an introductory text and aiming to facilitate the understanding of the field to non-experts, this part does not dwell on the set of topics, such as cellular mechanosensing and mechanotransduction, irreversible EP, and atomistic molecular dynamics modelling of membrane EP.

by Julien Berro (Author), Michael M Lacy (Author), Wallace F Marshall (Editor)
Clathrin-mediated endocytosis (CME) is a ubiquitous internalization process in eukaryotic cells. It consists of the formation of an approximately 50-nm diameter vesicle out of a flat membrane.

This book provides a brief overview of single-cell analysis using recent advanced technologies.
The different sections cover different aspect of single cell analysis and applications with their advantages, limitations, and future challenges. The book has covered how different physical energies such as optical, electrical, and mechanical energy have been applied for single cell therapy and analysis.