Tumour

This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy.

The knowledge of molecular defects that lead to cancer is increasing rapidly. This has created a need for a textbook that conveys a comprehensive review of this topic. "Molecular Mechanisms of Cancer", describes molecular processes whose deregulation is important in the formation of tumours. The material is developed from basic cell signalling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumour cells (leading to growth deregulation, extended lifespan, and the ability to invade surrounding tissue), protective mechanisms that prevent transformation (including DNA repair and epigenetic regulation), tumour-host interactions (with the endocrine system, the immune system, and blood vessel formation), and the underlying molecular defects of individual cancers. This book is an essential resource for researchers, graduate students and oncologists. It will also aid in drug discovery by identifying molecular targets. The growing insight generated by research into molecular carcinogenesis and the absence of comparably comprehensive and systematic textbooks makes this publication important and timely.

Martin Albert Mulry (2 September 1947 – 1 September 2001), known professionally as Ted Mulry, was an English-born Australian singer, songwriter, bass player and guitarist. As a solo artist, his second single, "Falling in Love Again" (February 1971), reached No. 11 on the Go-Set National Top 60.

Martin Albert Mulry (2 September 1947 – 1 September 2001), known professionally as Ted Mulry, was an English-born Australian singer, songwriter, bass player and guitarist. As a solo artist, his second single, "Falling in Love Again" (February 1971), reached No. 11 on the Go-Set National Top 60.

Martin Albert Mulry (2 September 1947 – 1 September 2001), known professionally as Ted Mulry, was an English-born Australian singer, songwriter, bass player and guitarist. As a solo artist, his second single, "Falling in Love Again" (February 1971), reached No. 11 on the Go-Set National Top 60.