Comparative Biochemistry of Parasitic Helminths

Obesity is an independent risk factor for cardiovascular disease (CVD) in adults as well as in obese children. This book will provide a description of the impact of obesity on the cardiovascular system and increased predisposition to CVD.

At its present rate of growth, atherosclerosis will be the major cause of death from disease by the year 2020. Atherosclerosis is an extremely complex, biochemical, multifactorial process. This book will cover many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. We will cover all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. This book will explore the role of nuclear hormonereceptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. Finally, how the use of genetic studies can help sort out the immensecomplexities that mediate these aspects of atherogenesis will be discussed.

Cisplatin Chemistry and Biochemistry of a Leading Anticancer Drug Since Rosenberg’s serendipitous discovery of its antitumor activity, cisplatin has become one of the greatest success stories of cancer chemotherapy. The biomedical applications of this inorganic compound have had an enormous impact on the development of coordination chemistry, and have served to underline the critical importance of basic research.

Human blood performs many important functions including defence against disease and transport of biomolecules, but perhaps the most important is to carry oxygen – the fundamental biochemical fuel - and other blood gases around the cardiovascular system.